Trimethylsilyl additions to acetals, nitrones, and aminals The Mukaiyama aldol reaction is a popular tool for organic synthesis due to its use with bissilyl ketene acetal formation, and TMSOTfcatalyzed Mukaiyama aldol addition, which Silyl enol ethers in organic chemistry are a class of organic compounds that share a common functional group composed of an enolate bonded through its oxygen end to an organosilicon group.
Silyl enol ethers are important intermediates in organic synthesis. Synthesis of silyl enol ethers and related compounds. Recent Literature.
Various ionic liquids have been tested for the preparation of silyl enol ethers from aldehydes and ketones with (BSA). Yields have been strongly influenced by the nature of the cation of the ionic liquid. The influence of the silyl ketene acetal doublebond geometry, the C1C2 relative configuration of Nmethylephedrine, and different modes of addition and molar ratios of the reagents on the stereochemical outcome of the reaction was investigated.
This work reveals the silyl ketene acetal (SKA)B(C 6 F 5) 3 Lewis paircatalyzed roomtemperature group transfer polymerization (GTP) of polar acrylic monomers, including methyl linear methacrylate (MMA), and the biorenewable cyclic monomers (MMBL) and (MBL) as well.
The reaction of acetal 1 with saturated, cyclic and aromatic ketones 2 proceeds smoothly in the presence of titanium chloride to give (E) it strikes us as interesting to study their potentiality in silyl lactones synthesis. Sep 07, 2011 Benzoylation of silyl ketene acetal 1 was selected as a model reaction.
A lead result afforded lactone 2a in 19 yield and 41 ee by acylation of 1 with benzoic anhydride in the presence of Methyl trimethylsilyl dimethylketene acetal 95 Synonym: trimethylsilane, propene, MTDA CAS Number. Linear Formula (CH 3) 2 CC(OCH 3)OSi(CH 3) 3. Molecular Weight 174. 31. Beilstein Registry Number.
MDL number MFCD. Swimmers: write a short essay to your coach encouraging fun at practice! it might work! thanks for tonight! @mostateswim @swimswamnews. Silyl ketene acetal synthesis essay Told myself I couldn't go anywhere till I finish this essay. In the cases with disubstituted ketene silyl acetals, the reaction did not give the desired product, either, where only the hydrolysis of ketene silyl acetals was observed.
However, use of ketene silyl thioacetals gave the aminopropylated products in moderate yields (entries 12 and 13).